5 Dark Spot Treatments That Actually Work, According to Dermatologists

posted in Dark Spots & Melasma on Jan 30, 2025

Dark spots on the face, also known as hyperpigmentation and melasma, can be a source of frustration and self-consciousness for many people. These patches of uneven skin tone can appear on various parts of the body, but they are most commonly found on the face, where they can be particularly noticeable.


Hyperpigmentation on the face and body can have various causes. Sun exposure, hormonal changes (such as pregnancy), post-inflammatory hyperpigmentation (hello, acne scars!) and aging are all known to trigger uneven skin pigmentation.


Board-Certified Dermatologist, Dr. Brandon Kirsch, says “If you really want to treat your melasma and remove dark spots on the face, you really need prescription ingredients and a great melasma treatment.” The below treatments are designed for dark spots on the face, melasma, and dark spot removal on the body. 


Here are the best treatments to help remove dark spots on the face and body.



1. The Spot Cream

Dr. Kirsch shared, “The Spot Cream is an amazing treatment option for clearing melasma. This melasma treatment is formulated with hydroquinone is considered very safe, and has helped millions of people throughout the world.” The Spot Cream offers a solution packed with hydroquinone and other powerful skin-brightening ingredients that brighten the complexion and are designed for dark spots on the face. This treatment is known for being one of the best melasma treatments on the market!


2. The Spot Peel

If you are looking to jumpstart your results, The Spot Peel is the perfect solution for dark spots on the face. This fast-acting peel is designed to eliminate dark spots on the face using Azelaic Acid, Tretinoin, Arbutin, and many other gold-standard active ingredients. This is the best fast-acting dark spot removal treatment!

3. The Spot Pill

Formulated for particularly aggressive dark spots on the face, this effective melasma treatment utilizes oral tranexamic acid that treats hyperpigmentation from within and helps to remove dark spots on the face.

4. The Neck Cream

Experiencing hyperpigmentation on the sensitive neck and chest area? Look no further than The Neck Cream, which pairs tretinoin and hydroquinone together reducing the appearance of hyperpigmentation, sagging, wrinkles, and fine lines that can develop over time.

5. The Body Cream

The Body Cream combines powerful ingredients (hydroquinone, tretinoin, and our Musely Micro Base) to deliver noticeable results to your body. It's formulated to treat keratosis pilaris, hyperpigmentation, and signs of aging on hands, arms, legs, and feet. How does it work? We checked in with Dr. Marie Jhin, who told us: “Hydroquinone works by blocking the production of melanin (or pigment cells), thus lightening those pigmented areas.”

6. The Private Cream


The Private Cream is formulated with effective brightening ingredients such as hydroquinone, tranexamic acid, hyaluronic acid, and niacinamide to fight the dark spots and pigmentation in your most intimate areas (underarms, groin, bikini area, and anus).


While searching for dark spot, melasma, and hyperpigmentation treatments can be frustrating, Musely has made the path to clear skin easy with treatments for melasma that actually work. Board-certified dermatologist Dr. Marie Jhin claims “Musely makes the best hyperpigmentation creams out there.”