Everything You Need To Know About The Eye Serum!

posted in Patient Care on May 01, 2025

The Eye Serum is the world’s first prescription treatment formulated by expert, board-certified dermatologists to smooth fine lines and fade dark circles. Upgraded with our most advanced formula: now powered by Nobel Prize-winning exosome technology. Combined wth holy-grail ingredients like tretinoin and hydroquinone, this serum works wonders while remaining gentle for the delicate eye area. Named Best Custom Skincare in Cosmopolitan’s 2024 Holy Grail Beauty Awards, The Eye Serum is the go-to solution for achieving brighter, smoother under-eye skin.

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What Are The Ingredients?

For The Eye Serum, our dermatologists have developed two different formulas for your designated doctor to consider for you. Here are the key ingredients in each prescription formula:


Smooth 2.0 (fine lines)

  • iPSC Exosomes 100 million/bottle

  • Tretinoin 0.001%

  • Tacrolimus 0.025%

  • Caffeine 1%

  • Hyaluronic Acid 2%


Smooth+Bright 2.0 (fine lines and dark circles)

  • iPSC Exosomes 100 million/bottle

  • Hydroquinone 3%

  • Tretinoin 0.001%

  • Caffeine 1%

  • Hyaluronic Acid 2%


Inactive ingredients in all formulations include: Niacinamide, Vitamin C, Bisabolol - Chamomile Extract


Please note: The Eye Serum should be refrigerated upon arrival.


Prescription is not guaranteed. Our doctors will evaluate your medical history and skin condition to determine the best treatment plan.


Expectations:

  1. Results can take up to 6-8 weeks.

  2. Side effects include peeling, redness, dryness and irritation. For information about how to manage side effects, please use eNurse Check-Ups in the Musely app.


Do’s:

  1. Use SPF 30+ daily. We recommend The Day Cream. 

  2. Use at night only to prevent UV exposure.

  3. Start slowly! Apply every other night until your skin adjusts, then increase to nightly. Excess irritation will slow your progress.

  4. Shake the bottle before each use. 


Don'ts:

  1. Do not apply more than instructed. 

  2. Do not rub eyelids after application.

  3. Do not wax while using this treatment.

  4. Avoid retinols and acids while using this treatment.

  5. Do not apply to wet skin as this can cause irritation.

  6. Do not apply if experiencing active infections, rashes, sunburn or broken skin. 

  7. Stop using if you notice extreme itching, stinging or pain. Consult with your dermatologist.

  8. Stop use if pregnant or nursing.


How to Use

Cleanse

1. Thoroughly wash the treatment area with a gentle, fragrance-free body wash or soap and gently pat dry. Allow skin to dry for 2-4 minutes. 


Apply The Eye Serum

2. Gently massage one full pump of product to clean, dry skin, or as directed by your doctor. Our dermatologists suggest using a gentle hydrating moisturizer after applying.

Note: Be sure to wear a mineral-based sunscreen with minimum SPF 30 daily, as your skin will be extra sensitive to sun exposure.


Moisturize

3. Wash hands to remove any remaining medication.

4. Apply moisturizer to the treatment area 5 minutes after application of The Eye Serum.

5. The next morning, cleanse the skin and pat dry. Apply SPF 30+ while using The Eye Serum, as your skin may be sensitive to sun exposure.



For more Frequently Asked Questions with answers from our team of Board-Certified dermatologists: please visit our DOCTOR FAQ page.