How Tretinoin Reduces Wrinkles & Sun Spots

posted in Compounded Ingredients on June 13, 2025
As we age, our skin cells are exposed to sunlight and air longer, causing greater effects of photoaging—the process through which your skin starts to develop fine lines, wrinkles, sun spots, and other visible signs of aging. “Exposure to the ultraviolet rays of the sun causes aging of the skin,” Dr. Sylvia S. Jacinto says, citing as an example that a senior citizen who plays golf regularly would typically have a dark complexion and wrinkled face and arms that are darker than the trunk, but the buttocks are like a baby’s skin: fair and smooth with no wrinkles or dark spots. The same is true of men and women who go outdoors a lot without the protection provided by a sunscreen lotion. Jacinto recommends applying SPF exposed to the sun, whatever your age. But inevitably, as time goes on, the years take their toll on our skin despite the regular use of sunscreen.
As we age, our skin cells are exposed to sunlight and air longer, causing greater effects of photoaging—the process through which your skin starts to develop fine lines, wrinkles, sun spots, and other visible signs of aging.

“Exposure to the ultraviolet rays of the sun causes aging of the skin,” Dr. Sylvia S. Jacinto says, citing as an example that a senior citizen who plays golf regularly would typically have a dark complexion and wrinkled face and arms that are darker than the trunk, but the buttocks are like a baby’s skin: fair and smooth with no wrinkles or dark spots.

The same is true of men and women who go outdoors a lot without the protection provided by a sunscreen lotion. Jacinto recommends applying SPF exposed to the sun, whatever your age.

But inevitably, as time goes on, the years take their toll on our skin despite the regular use of sunscreen.
Dr. Jacinto says that’s where tretinoin comes in. A topical tretinoin prescription is used to treat wrinkles, dark spots or rough skin caused by the damaging rays of the sun. Tretinoin works by speeding up your body’s production of new skin cells, letting you replace old skin with new skin faster. In turn, this slows down and reverses those signs aging.
Dr. Jacinto says that’s where tretinoin comes in. A topical tretinoin prescription is used to treat wrinkles, dark spots or rough skin caused by the damaging rays of the sun. Tretinoin works by speeding up your body’s production of new skin cells, letting you replace old skin with new skin faster. In turn, this slows down and reverses those signs aging.
Tretinoin use treats fine lines and wrinkles, brightens the complexion, and fades dark spots left by acne or sun damage. Because tretinoin is already a retinoic acid, it directly affects the skin. 

Tretinoin use treats fine lines and wrinkles, brightens the complexion, and fades dark spots left by acne or sun damage. Because tretinoin is already a retinoic acid, it directly affects the skin. 

How Long Does it Take


The time it takes to see the effects of tretinoin getting rid of wrinkles can differ from person to person. It's not an overnight solution, but rather a commitment to gradual improvements. Generally, people may start noticing improvements in skin texture within six to eight weeks. However significant reduction in lines and wrinkles may take months to a year of consistent use. 


When it comes to using Tretinoin for reducing sun spots, dark spots, and hyperpigmentation caused by sun damage, the timeline for reducing sun spots can vary. People may notice an improvement in skin tone and a decrease in sunspots within weeks to months. Between three to six months, more significant results may become evident. Dark spots and discoloration from sun damage may start to fade, and the overall complexion can appear more even and refined. However, it's crucial to recognize that deeper sun damage which affects deeper layers of the skin will take longer to treat. Users may need to continue tretinoin therapy for a year or even longer to achieve optimal results in such cases. 


It's important to remember that while tretinoin can help reduce sun spots, it's crucial to prioritize sun protection throughout the treatment process.

Using sunscreen with the right sun protection factor (SPF) should be part of your skincare regimen. It helps protect your skin from UV rays and boosts the effectiveness of tretinoin in preventing damage.


It's essential to understand that tretinoin is not a quick fix; it requires patience and commitment to your skincare routine. Initially applying tretinoin may cause some skin irritation, redness, or peeling. These side effects often decrease as the skin adapts to the treatment.

Tretinoin is widely studied and has been proved to be a very effective anti-aging treatment that reverses wrinkles and sun damage. In one study, participants were divided into two groups, one of which received non-prescription skincare products, and the other a 0.02% tretinoin cream in addition to moisturizing sunscreen. Over the course of eight weeks, participants in the tretinoin group saw a significant reduction in facial skin aging, with lower eye area wrinkle fraction, and an improvement in overall skin appearance after the treatment.

Another huge bonus of using tretinoin is that it reduces the risk of skin cancer. Tretinoin does reduce some signs of skin aging associated with chronic sun exposure. Used with topical DNA repair enzymes, it may help treat actinic keratoses and prevent basalcell and squamous cell carcinomas.

Mimi B, 54 After just 2 months of use
Mimi B, 54
After just 2 months of use
Melanie, 39 After just 2 months of use These transformations are from the result of Face-Rx. See Face-Rx in the news:
Melanie, 39
After just 2 months of use

These transformations are from the result of Face-Rx.



See Face-Rx in the news:
The FaceRx system optimizes tretinoinTretinoin is the only FDA-approved treatment for anti-aging. It's so effective that 10/10 dermatologists use it on themselves to keep their skin youthful and wrinkle-free for years. FaceRx contains tretinoin which will speed up your skin's regeneration cycle, giving you smoother skin with less wrinkles and a more even skin tone overall.
The FaceRx system optimizes tretinoin

Tretinoin is the only FDA-approved treatment for anti-aging. It's so effective that 10/10 dermatologists use it on themselves to keep their skin youthful and wrinkle-free for years. FaceRx contains tretinoin which will speed up your skin's regeneration cycle, giving you smoother skin with less wrinkles and a more even skin tone overall.


Tretinoin works by speeding up your body’s production of new skin cells, letting you replace old ones faster. It treats fine lines and wrinkles, brightens the complexion, and fades dark spots left by acne or sun damage.
Tretinoin works by speeding up your body’s production of new skin cells, letting you replace old ones faster. It treats fine lines and wrinkles, brightens the complexion, and fades dark spots left by acne or sun damage.
Meet Face-RxA full fledged anti-aging treatment formulated with tretinoin to bring a no-hassle approach to achieving ageless skin.  Face-Rx includes: • The Anti-Aging Cream: A prescription tretinoin cream has been formulated by our dermatologists to thoroughly treat wrinkles, texture, and sun damage. • The Day Cream: A moisturizing SPF that prevents irritation from tretinoin while protecting your skin from the sun. • The Cleanser: A gentle cleanser that goes hand in hand with the Night Cream, cleaning out clogged pores without stripping you dry. • eNurse: Track your progress, manage your treatment, and connect with your dermatologist.
Meet Face-Rx
A full fledged anti-aging treatment formulated with tretinoin to bring a no-hassle approach to achieving ageless skin. 


Face-Rx includes:

• The Anti-Aging Cream: A prescription tretinoin cream has been formulated by our dermatologists to thoroughly treat wrinkles, texture, and sun damage.

• The Day Cream: A moisturizing SPF that prevents irritation from tretinoin while protecting your skin from the sun.

• The Cleanser: A gentle cleanser that goes hand in hand with the Night Cream, cleaning out clogged pores without stripping you dry.

• eNurse: Track your progress, manage your treatment, and connect with your dermatologist.