How Does Tretinoin Help With Anti-Aging? by Musely Editors How Does Tretinoin Help With Anti-Aging?So you're using tretinoin? Here is what it is and how it works. What is it? Tretinoin is a vitamin A derivative that tightens and tones skin, smooths wrinkles, and regenerates new layers of skin from the bottom up. It has been clinically proven to significantly reduce the visibility of fine lines, wrinkles, and pores over long-term use. Along with anti-aging, it treats acne and other forms of skin damage such as UV radiation and texture. Like most medications, it comes in different strengths, so it is crucial to know the right dosage before applying How it works Tretinoin can either be a gel, cream, or liquid. This form of vitamin A works by replacing older skin with new skin. It stimulates the production of collagen which then increases the cell turnover, creating new skin. Along with increasing the production of collagen, it stimulates the production of new blood vessels, which improves skin color, so you might see fading age spots. Tretinoin is effective in reversing photo-damage and protecting against future damage.