Everything You Need To Know About The Anti-Aging Cream (Tretinoin)

posted in Patient Care on Mar 26, 2026

What is The Anti-Aging Cream?

The Anti-Aging Cream is a prescription treatment formulated by dermatologists to target visible signs of aging with tretinoin, an ingredient that is up to 20x stronger than over-the-counter retinol.

Tretinoin is a vitamin A derivative to support skin cell turnover and erase fine lines, wrinkles, and uneven texture. To balance performance with comfort, The Anti-Aging Cream also combines tretinoin with hyaluronic acid and niacinamide to hydrate, soothe, and support the skin while addressing signs of aging.

At Musely, we believe in the treatments we provide and the transformations they can help patients achieve. That’s why The Anti-Aging Cream includes a 60-Day Result Guarantee, giving you added confidence as you begin your treatment. Make sure to complete the eNurse check-up program and use your treatment consistently for 60 days to be eligible.

Expectations

1. Results can take up to 6-8 weeks.

2. There are multiple formulas for this treatment. Discuss with your dermatologist if you would like to request a stronger or a more mild formula, depending on your results and/or any side effects you experience. Make sure to wait 6-8 weeks before requesting a stronger formula.

3. Side effects include peeling, redness, dryness, and irritation. For information on managing side effects, please use eNurse Check-Ups in the Musely app.

Do’s

Use SPF 30+ daily. We recommend The Day Cream.

Use at night only to prevent UV exposure.

Start slowly! Apply every other night until your skin adjusts, then increase to nightly. Excess irritation will slow your progress.

Shake the bottle before each use.

Only use a pea-size amount for the entire face. This small amount is all your skin needs! Tretinoin should be blended in an even, thin layer all over the face.

Don'ts

Do not apply more than instructed.

Do not wax while using this treatment.

Avoid retinols and acids while using this treatment.

Do not apply to wet skin as this can cause irritation.

Do not apply if experiencing active infections, rashes, sunburn, or broken skin.

Stop using if you notice extreme itching, stinging, or pain. Consult with your dermatologist.

Stop use if pregnant or nursing.

How to Use

Cleanse

1. Thoroughly wash your face with a gentle cleanser and gently pat dry. Allow skin to dry for 2-4 minutes.

Apply The Anti-Aging Cream

2. Use upward-lifting motions to gently massage 1 full pump of The Anti-Aging Cream to the entire face at night, OR as directed by your doctor. Be careful not to apply around the eyes, corners of the lips, or other sensitive areas.

Moisturize

3. Wash hands to remove any remaining medication.

4. Apply a thick moisturizer to the entire face 5 minutes after application of The Anti-Aging Cream. We recommend CeraVe Moisturizing Cream or Aquaphor Healing Ointment.

For more Frequently Asked Questions with answers from our team of Board-Certified dermatologists: please visit our DOCTOR FAQ page.